These interactions are particularly significant when theophylline serum concentrations are already in the high … As you'll see in this eMedTV segment, theophylline can interact with a number of other medications, such as alcohol, allopurinol, and certain antibiotics and seizure drugs. Manufacturer makes no recommendation. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine … Take consistently with regard to food. Introduction. The clinical significance of drug-food interactions can be variable. In the given example, reacting N,N-dimethylurea with cyanoacetic ether in the presence of acetic anhydride gives … Please refer to the local prescribing information. When consumed with certain foods, Ketotifen + Theophylline may take longer to have an effect. Induction of CYP1A2 results in a more rapid clearance of theophylline, which leads to reduced, and most likely sub-therapeutic, serum theophylline concentrations. Sustained-release forms of theophylline should be taken on an empty stomach and should not be crushed or chewed. It helps open up the airways in your lungs to make it easier to breathe. Theophylline controls symptoms of asthma and other lung diseases but … The release of theophylline from sustained-release dosage forms can be influenced (either increased or decreased) by concomitant intake of food. The following interactions have been selected on the basis of their potential significance and are not … Theophylline drug interactions can alter the level of theophylline in your blood or make some drugs less effective, among other things. Severity of interaction: Generally, the effect of food Interactions between theophylline and other medications Theophylline may interact with certain medications or supplements. Food greatly decreases isoniazid bioavailability. Theophylline’s uses include preventing and treating wheezing, coughing, shortness of breath and chest tightness typically experienced … Theophylline is a prescription bronchodilator treatment for cats and dogs, used to open air passages in the lungs by relaxing the muscles in the lungs and chest. Interaction between Food and Ketotifen + Theophylline. ~40% plasma protein binding Apparent Vd =0.45 L/kg (range 0.3 -0.7 L/kg) in both non-obese and obese subjects -- widely distributed into extracellular water and muscle tissue, increases linearly with TBW because of increase in EC water that also happens with addition of fat tissue The labeling for theophylline products states that theophylline clearance may be decreased by up to 35% when clarithromycin is prescribed concurrently; these interactions can be clinically important. An interaction is when a substance changes the way a medication works. Contact your doctor about this. Liquid and non-sustained release theophylline products are best taken on an empty stomach, but they may be taken with food … This medicine is used to treat the symptoms of asthma, bronchitis, and emphysema. This can be harmful or prevent the drug from working well. Ketotifen + Theophylline Interactions with Food and Alcohol . Using alcohol or tobacco with certain medicines may also cause interactions to occur. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) … theophylline . 8 . Do not take the following drugs with theophylline unless you have consulted with your doctor: thiabendazole, St. John's Wort, rifampin, propranolol, fluvoxamine, … Does omalizumab interact with any other medications? Special attention is paid to the specific (bio)pharmaceutical characteristics of the different products, and to the influence of the composition … Clinical Pharmacokinetics 16: 162–179, 1989 PubMed CrossRef Google Scholar Jusko WJ, Schentag JJ, Clark JH, Gardner M, Yurchak AM. It works in the airways by relaxing muscles, opening breathing passages, and decreasing the … Avoid St. John's Wort. Coadmininstration with drugs that decrease theophylline clearance (eg, cimetidine, ciprofloxacin, and erythromycin and other macrolides): 0.2-0.3 mg/kg/hr IV or PO (extended release) q12-24hr Congestive heart failure: 0.39 mg/kg/hr IV for next 12 hours after loading dose, then 0.08-0.16 mg/kg/hr Interaction between foods and drugs can have profound influence on the success of drug treatment and on the side effect profiles of many drugs. Used in the systemic treatment of obstructive airway diseases., ... Overdosage Drug Interactions Food Interaction Lab Interference Action Storage CIMS Class ATC Classification. Whatever the mechanism, the interaction may be sufficient to necessitate adjustment of the theophylline … To reduce the risk of developing potentially dangerous drug interactions with theophylline, you should talk with your healthcare provider or pharmacist about any theophylline interactions … Many drugs interact with theophylline by inhibiting or potentiating its metabolism by CYP1A2 (see ’Commonlyused drugs that interact with theophylline’). With some preparations the composition of the meal, especially its fat content, determines the degree of the food … Adult: Individualise dosing based on serum theophylline levels; use ideal body weight to calculate dose.As adjunct to inhaled β 2-agonists and systemic corticosteroids for the treatment of acute exacerbations of symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases: As theophylline … Theophylline should be administered 2 to 3 times a day and the suggested dosage for dogs is 2.25 to 5 grams of medication per pound of weight of the pet. This information is not country-specific. Elixophyllin (theophylline) is an inhaler used to relieve and prevent airway narrowing (bronchospasm) for people with asthma, emphysema, and chronic bronchitis. A review is given of those food interactions with the sustained-release theophylline preparations, both twice-daily and once-daily products, that are currently on the world market. theophylline (some forms are regular release, sustained release, and sprinkles). Theophylline helps improve breathing in those suffering from asthma, chronic bronchitis, emphysema and other lung diseases.. Pronunciation: thee-OF-i-lin What are theophylline’s uses? To avoid an interaction, be sure your doctor knows what prescription drugs you are taking as well as any vitamins, supplements and over-the-counter medicines. Extended-release capsules (e.g., Theo-Dur Sprinkles) may be swallowed whole or opened and the contents mixed with soft food and swallowed without chewing. Dosage and Administration of Theophylline. More About this Book. Ingesting alcohol may reduce the clearance, and therefore increase the serum concentrations of theophylline. Theophylline is predicted to cause hypokalaemia (potentially increasing the risk of torsade de pointes) when given with arsenic trioxide. Take the extended-release capsule or tablet every morning at the same time each day. Theophylline may interact with other medications. High carbohydrate foods because they decrease theophylline absorption. Theophylline (Elixophyllin, Theo-24) is a bronchodilator prescribed for the treatment of asthma and other airway conditions. ... Drug, Food, and Test Interactions Consult your veterinarian before using theophylline with phenobarbital, phenytoin, cimetidine, erythromycin, allopurinol, … Provides a summary of interactions with vitamins, herbs, and food Check with your pharmacist to be sure you know which form of the medicine you use The medication should be administered on an empty stomach and food should be given an hour after the administration of the … Other integrated mechanisms (e.g., hepatic uptake) may also be altered by concurrent administration of other drugs. Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. Food interactions with sustained-release theophylline preparations: a review. Serious side effects of Elixophyllin include … Obviously, ultra-slow-releasing products are most vulnerable to food effects. High-carbohydrate, low-protein diets can increase theophylline activity and side effects. Theophylline Accession Number DB00277 Description. Take with or without food. This page describes these interactions and explains how … ... Food Interactions. Interactions Food: Food can have different effects on different forms of . High fat foods because they increase theophylline absorption. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. THEOPHYLLINE is a bronchodilator. Keep all appointments for testing the blood level. Interactions. PIP: Since up to 90% of a theophylline dose is biotransformed, drugs influencing microsomal enzyme systems in the liver may affect the elimination of theophylline. After you or your child begin taking theophylline, it is very important that your doctor check the level of the medicine in the blood at regular intervals to decide if the dose needs to be changed. Theophylline oral tablet can interact with other medications, vitamins, or herbs you may be taking. Theophylline, 1,3-dimethylxanthine (23.3.5), is present in small quantities in tea leaves.It is synthesized synthetically by the Traube method, a general method suggested for making purine bases. The lowest GoodRx price for the most common version of theophylline ER is around $63.80, 78% off the average retail price of $297.84. Food and drugs are essential components of the patient’s therapeutic plan. Theophylline + Aminophylline Interactions with Food and Alcohol Interaction between Food and Theophylline + Aminophylline Due to a lack of research, nothing can be said about the consequences of taking Theophylline + Aminophylline together with food. Common side effects of Elixophyllin include nausea, vomiting, diarrhea, headaches, irritability, flushing, and palpitations. The oral theophylline tablet may interact with other medications, vitamins or herbs you may be taking. In relatively high doses, isoniazid can also cause increased effect of theophylline and warfarin. Isoniazid inhibits metabolism of selected benzodiazepines and vitamin D. Inhibition of monoamine oxidase and histaminase by isoniazid can cause significant drug-food interactions. Theophylline: Belongs to the class of xanthines. Swallow the extended-release tablets whole; do not chew or crush them. Drug/Food Interactions Taking Theo-24 ® less than one hour before a high-fat-content meal, such as 8 oz whole milk, 2 fried eggs, 2 bacon strips, 2 oz hashed brown potatoes, and 2 slices of buttered toast (about 985 calories, including approximately 71 g of fat) may result in a significant increase in peak serum level … Drug-food interactions can lead to a loss of therapeutic efficacy or toxic effects of drug therapy. 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